Our Published Research...

Over 35 Years of Published Research...
An Important Independent Compendium of Our Scientific Research & Clinical Studies by Anton Kutikhin, PhD in The International Journal of NanoMedicine entitled “The Role of CNPs in Biology & Medicine” www.ncbi.nlm.nih.gov/pmc/articles/PMC3266001

(Please note that for publishing purposes, Dr. Gary Mezo's Nanobiotics were referred-to as comET as a non-branded generic name and not our actual brand names of NanobacTX, Urobac or RegenurEYES. Scientific publications allow only the use of generic names and not trademark names.) Most listed papers may be found at GOOGLE SCHOLAR.

Published Science & Clinical Studies/Clinical Trials:

1. Maniscalco, B.S., NanobacTX Cardiology Study. Journal of Pathophysiology.11(2): 95-101. www.pathophysiologyjournal.com/article/S0928-4680(04)00079-3/fulltext

2. Puskas, L. G., L. Tiszlavicz, Zs Razga, L. Torday, T. Krenacs, J. G Papp. Detection of nanobacteria-like particles in human atherosclerotic plaques. Acta Biologica Hungarica56 (3-4): 233-245.www.ncbi.nlm.nih.gov

3. Jelic T. M., A. M. Malas, S. S. Groves, B. Jin, P. F. Mellen, G. Osborne, R. Roque, J. G. Rosencrance, and H. H. Chang. Nanobacteria-caused mitral valve calciphylaxis in a man with diabetic renal failure.South Med J.Feb; 97 (2): 194- 198.

4. Lieske J. C., V. Kumar, G. Farell-Baril, S. Yu, J. E. Charlesworth, E. Rzewusk-Lech, P. LaBreche, S. R. Severson, and V. M. Miller. Mayo Clinic.Detection and propagation of calcified nanostructures from human aneurysm.J Am Coll Cardiol Abstracts Book.1059-13: 13A.

5. Miller, V. M., G. Rodgers, J. A. Charlesworth, B. Kirkland, S. R. Severson, T. E. Rasmussen, M. Yagubyan, J. C. Rodgers, F. R Cockerill, III, R. L. Folk, V. Kumar, G. Farell-Baril, J. C. Lieske. MAYO CLINIC. Evidence of nanobacterial-like structures in human calcified arteries and cardiac valves. Am J Physiol Heart Circ Physiol.287 (3): H1115-24.www.ncbi.nlm.nih.gov

6. Kajander, E O.Nanobacteria do exist and actively participate in the calcification of arterial plaque.Townsend Letter 234:80-82.

7. Ciftcioglu, N., M. A. Miller-Hjelle. J. T. Hjelle and E. O. Kajander. Inhibition of Nanobacteria as measured by a modified microdilution method.Antimicrob Agents Chemother.46: 2077-2086.

8. Kajander, E. O., K. Aho and V. Segal. Apatite biofilm forming agent: nanobacteria as a model system for biomineralization and biological standard for noa, a preliminary study.Proceedings of the 2nd International Conference on Near-Field Optical analysis. Houston, Texas.

9. Rasmussen, T. E., B. L. Kirkland, J. Charlesworth, et al.Electron microscope and immunological evidence of nanobacteria in calcified carotid arteries, aortic aneurysms and cardiac valves.J Am Coll Cardiol Abstracts Book.1009-79: 206A.

10. Ciftcioglu, N., V. Ciftcioglu, H. Vali, E. Turcott, E. O. Kajander. Sedimentary rocks in our mouth: dental pulp stones made by nanobacteria. Proc. SPIE.3441: 130-135.

Studies specific to Pathological Calcification & Nanobacteria:

1. Kajander EO; Nanobacteria – propagating calcifying nanoparticles. Lett Appl Microbiol. 2006 Jun; 42(6):549-52.

2. Tsurumoto T., T. Matsumoto, A. Yonekura, and H. Shindo; Nanobacteria in Human Arthritic Synovial Fluids. Journal of Proteome Research. ASAP Article 10.1021/pr050450w S1535-3893(05)00450-1 [April 8, 2006] American Chemical Societypubs.acs.org 

3. Ciftioglu N; Nanobacteria-Discovery of a new form of life. Horizons 2006 March 31: 7-8. www.aiaa-houston.org/newsletter

4. Sommer, AP; Wichramasinghe, NC. Functions and Possible Provenance of Primordial Proteins-Part II: Microorganism Aggregation in Clouds Triggered by Climate Change. Journal of Proteome Research. 4: 180-184, 2005. 

5. Sommer, AP; Pretorius, AM; Kajander, EO and Oron, U. Biomineralization induced by stressed nanobacteria. Crystal Growth & Design. 2004. (1): 45-46. 

6. Wang, XJ, et al. 2004. The detection of nanobacteria infection in serum of healthy Chinese people. Zhonghua Liu Xing Bing Xue Za Zhi. 25(6):494-4.

7. Wilk, IG, Martirosian, KZ; Mikrobiologii, S. A. Medycznei, Khatowice. 2004. Nanobacteria microbiological characteristics. Postepy Hig Med Dosw (online), 2004; 58: 60-64.

8. Aho K, Kajander EO. 2003. Detection of Novel Nanoorganisms .J Clin Microbiol. 41(7): 3460-3461. 

9. Barr SC, Linke, SE, et al. 2003. Detection of biofilms formation and nanobacteria under long-term cell culture conditions in serum samples of cattle, goats, cats and dogs. Am J Vet Res. 64(2):176-182.

10. Miller-Hjelle, MA; Hjelle, JT; Ciftcioglu, N; Kajander, EO. 2003. Nanobacteria: methods for growth and identification of this recently discovered calciferous agent. Rapid Analytical Microbiology. The chemistry and physics of microbial identification. Ed. . Olson. PDA, Bethesda, MD, USA. 297-312. 

11. Sommer, AP, McKay, DS; Ciftcioglu, N; Oron, U; Mester, AR; Kajander, EO. 2003. Living nanovesicles-chemical and physical survival strategies of primordial biosystems. Perspectives, J. Proteome Res. 2:441-443.

12. Ciftcioglu, N., Miller-Hjelle, MA; Hjelle, JT; Kajander, EO. 2002. Inhibition of nanobacteria as measured by a modified microdilution method. Antimicrob Agents Chemother. 46: 2077-2086.

13. Kajander, EO; Aho, K; Segal, V. 2002. Apatite biofilm forming agent: nanobacteria as a model system for biomineralization and biological standard for noa, a preliminary study. Proceedings of the 2nd International Conference on Near-Field Optical analysis: Photodynamic Therapy & Photobiology Effects. Houston, TX.

14. Sommer AP, Hassinen, HI; Kajander, EO. 2002. Light-induced replication of nanobacteria: a preliminary report. J Clin Laser Med Surg.20(5):241-244.www.ncbi.nlm.nih.gov

15. Sommer, A. P., U. Oron, E. O. Kajander and A. R. Mester. 2002. Stressed cells survive better with light. J. Proteome Res.1:475. 

16. Breitschwerdt, EB, Sushama, S, Cannedy, A, Hancock, SI, Bradley, JM. 2001. Infection with Bartonella weissii and Detection of Nanobacteria Antigens in a North Carolina Beef Herd Journal of Clinical Microbiology. 879-882. 

17. Vali, H; McKee, DM; Ciftcioglu, N; Kajander, EO; Sears, SK; et al. 2001. Nanoforms: a new type of protein-associated mineralization. Geochim.Cosmochim. Acta. 65:63-74. 

18. Ciftcioglu, N; Kajander, EO. 2000. Nanobacterial Growth Factors Proc. SPIE. 3755: 113-119. 

19. Kajander, EO; Ciftcioglu, N. 2000. Nanobacteria as Extremophiles Proc. SPIE. 3755: 106-112. 

20. Vainshtein MB; Kudriashova, EB. 2000. About Nanobacteria. Mikrobiologiia (Russian). 69(2):163-174. www.ncbi.nlm.nih.gov

21. Ciftcioglu, N. 1999. Microbial Presence vs Pathogenicity: Pleomorphic Microbes in Health and Disease. Proceedings of the first annual symposium held June 18-19. Edited by: Gitte S. Jensen Ph.D. Holger N.I.S. Inc.; 49-53. 

22. Kajander, EO; Bjorklund, M; Ciftcioglu, N. 1999. Nanobacteria and Man: Enigmatic Microorganisms and Life in Extreme Environments. Eds.J. Seckbach, Kluwer (the Netherlands). 195-204. 

23. Kajander, EO. 1999. Nanobacteria: Pleomorphic microbes in health and disease. Proceedings of the first annual symposium held June 18-19, 1999. Edited by: Gitte S. Jensen Ph.D. Holger N.I.S. Inc. Hudson, Quebec; 43-48. 

24. Kajander, EO; Heinonen, T; Kuronen, I; Luoto, K; Ciftcioglu, N. 1999. A New Problem for Sterile Filtration: Nanobacteria. Proceedings, WorldPharm. 99, October 26-28, 1999, Philadelphia. Advanstar Communications, Cleveland, OH. Pp. 243-252. 

25. Kajander, EO; T. Heinonen, I. Kuronen, K. Luoto, N. Ciftcioglu. Nanobacteria, mycoplasma and bacterial l-forms; problems for sterile filtration. 30th R3. Nordic Contamination Control Symposium.Helsinki, Finland. 

26. Southam, G., R. Donald. 1999. A structural comparison of bacterial microfossils vs. nanobacteria and nanofossils. Earth-Science Reviews.48 (4): 251-264.

27. Wainwright, M. 1999. Nanobacteria and associated elementary bodies in humans. Microbiology. 145: 2623-2624. 

28. Bjorklund, M., N. Ciftcioglu, E. O. Kajander. 1998. Extraordinary survival of nanobacteria under extreme conditions. Proc. SPIE. 3441: 123-129. 

29. Carson, DA. 1998. An Infectious Origin of Extraskeletal Calcification. PNAS.95: 7846-7847. 

30. Ciftcioglu, N., E. O. Kajander. 1998. Interaction of nanobacteria with cultured mammalian cells. Pathophysiology. 4: 259-270.

31. Ciftcioglu, N., M. Bjorklund, E. O. Kajander. 1998. Stone formation and calcification by nanobacteria in human body. Proc. SPIE.3441: 105-111. 

32. Kajander, E. O., M. Bjorklund, N. Ciftcioglu. 1998. Suggestions from observations on nanobacteria isolated from blood. Size limits of very small microorganisms: proceedings of a workshop, steering group on astrobiology of the Ciftcioglu, N., M. Bjorklund, K. Kuorikoski, K. 

33. Kajander, E. O., N. Ciftcioglu, M. Bjorklund. 1998. Mineralization by nanobacteria Proc. SPIE. 3441: 86-94. 

34. Kajander, E. O., N. Ciftcioglu. 1998. Nanobacteria: An alternative mechanism for pathogenic intra- and extracellular calcification and stone formation Proc. Natl. Acad. Sci. USA 95: 8274-8279. 

35. Akerman, K. K., J. T. Kuikka, N. Ciftcioglu, J. Parkkinen, K. A. Bergstrom, I. Kuronen, and E. O. Kajander. 1997. Radiolabeling and in vivo distribution of nanobacteria in rabbit. Proc. SPIE. 3111: 436-442. 

36. Ciftcioglu, N., A. Pelttari, E. O. Kajander. 1997. Extraordinary growth phases of nanobacteria isolated from mammalian blood. Proc. SPIE. 3111: 429-435. 

37. Cifcioglu, N., I. Kuronen, K. Akerman, E. Hiltunen, J. Laukkanen, E.O. Kajander, et al. 1997.A new potential threat in antigen and antibody products: nanobacteria. Cold spring harbor laboratory. Vaccines 97. 99-103. 

38. Kajander, E. O., I. Kuronen; K. Akerman, A. Pelttari, N. Ciftcioglu. 1997. Nanobacteria from blood, the smallest culturable autonomously replicating agent on earth. Proc. SPIE. 3111: 420-428. 

39. Kajander, E. O., E. Tahvanainen, I. Kuronen, N. Ciftcioglu. 1994. Comparison of staphylococci and novel bacteria-like particles from blood. Zbl. Bakt. (Suppl.) 26: 147-149. 

40. Akerman, K. K., I. Kuronen, and E. O. Kajander. 1993. Scanning Electron Microscopy of Nanobacteria: Novel Biofilm Producing Organisms in Blood. Scanning. 15 (Suppl.) 3:90-91. 
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
All Rights Reserved © NanobacTX.com